Search results for "antibody delivery"

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PEG-benzofulvene copolymer hydrogels for antibody delivery.

2010

A new amphiphilic copolymer have been synthesized starting from the hydrosoluble polyaspartylhydrazide (PAHy) polymer, by grafting both hydrophilic PEG(2000) chains and hydrophobic palmitic acid (C(16)) moieties on polymer backbone, and the structure of obtained PAHy-PEG(2000)-C(16) copolymer have been characterized by 2D (1)H/(13)C NMR experiments. PAHy-PEG(2000)-C(16) copolymer showed the ability of self-assembling in aqueous media giving a core-shell structure and resulted potentially useful for encapsulating and dissolving hydrophobic drug. The formation of micellar core-shell structure has been investigated by 2D (1)H NMR NOESY experiments. The presence of cross-peaks for protons of C(…

BiocompatibilityCell SurvivalPolymersSurface PropertiesPEG-benzofulvene immunoglobulin delivery hydrogelsimmunoglobulinsPharmaceutical SciencePolyethylene Glycolschemistry.chemical_compoundDrug Delivery SystemsCell Line TumorPolymer chemistryPEG ratioCopolymerHumansantibody deliverybenzofulvene copolymerschemistry.chemical_classificationChemistrytechnology industry and agricultureHydrogelsantibody delivery; benzofulvene copolymers; hydrogels; immunoglobulinsPolymerMacromonomerIndenesSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoImmunoglobulin GDrug deliverySelf-healing hydrogelsbenzofulvene copolymerhydrogelDrug Screening Assays AntitumorRheologyEthylene glycolInternational journal of pharmaceutics

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